iFluor® 560 Anti-human CD148 Antibody *MEM-CD148/05*
Catalogue Number: 114800A1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | MEM-CD148/05 |
| Isotype: | IgG2b |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: MEM-CD148/05 is an anti-human monoclonal antibody that forms an immune complex with the CD148 antigen. CD148 (sometimes called p260 or DEP-1) is a glycoprotein that is found on the surface of cells such as dendritic cells, platelets, B cells and NK cells. CD148 acts in key cellular pathways, for instance, the T cell receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway and positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis. In addition, in many organisms, it upregulates MAPK cascade, is an inhibitor of cell growth and represses cell migration. From a research standpoint, it is of biological interest due to its association with vital macromolecules/ligands. CD148 is a relatively rare antibody target, with fewer than 500 publications in the last decade. Even still, CD148 is typically used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 560 (ex/em = 560/571 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ Fusion).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
114800A1 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations