iFluor® 700 Anti-human CD150 Antibody *SLAM.4*
Catalogue Number: 115000J0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | SLAM.4 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: The SLAM.4 monoclonal antibody binds with human CD150, a 70 - 95 kD glycoprotein commonly located on the surface of B cells, dendritic cells, endothelial cells, T cells and Tregs. CD150 plays a role in important cellular pathways, in particular, the negative regulation of CD40 signaling pathway. In addition, in certain organisms, it is a negative regulator of tumor necrosis factor production, suppresses interleukin-6 production and plays a role in the upregulation of JNK cascade. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as tyrosine phosphatase CD45. CD150 is a fairly uncommon antibody target, with a little more than 2700 publications in the last decade. Even still, CD150 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, particularly in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
115000J0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations