Anti-AIF1 / Iba1 (Microglia Marker) Recombinant Mouse Monoclonal Antibody (Clone:rAIF1/1909)

Catalogue Number: 12-1063-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	Allograft inflammatory factor 1 (AIF1); balloon angioplasty responsive transcription (BART1); IBA1; Interferon responsive transcript 1; Ionized calcium-binding adapter molecule 1; IRT1; Microglia response factor (MRF1)
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rAIF1/1909
Isotype:	IgG1, kappa
Immunogen:	Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)
Application:	IHC

Overview
Datasheets

Description

Description: AIF1 is a cytoplasmic, calcium-binding protein that is thoµght to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Additional Text

Purification

Protein A/G Purified

Uniprot ID

P55008

Gene Name

AIF1

Gene ID

199

Application Notes

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Antibody Clonality

Monoclonal, Recombinant Monoclonal

12-1063 Datasheet

Price

£512.00

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