Anti-CD86 (Dendritic Cells Maturation Marker) Recombinant Mouse Monoclonal Antibody (Clone:rC86/1146)

Catalogue Number: 12-1131-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rC86/1146
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human CD86 protein
Application:	FACS, IF, IHC

Overview
Datasheets

Description

Description: Recognizes a protein of 70kDa, which is identified as CD86. CD86is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

Additional Text

Gene Name

CD86

Purification

Protein A/G Purified

Gene ID

942

Uniprot ID

P42081

Application Notes

Flow Cytometry (1-2µg/million cells);Immunofluorescence (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (2-4µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Antibody Clonality

Monoclonal, Recombinant Monoclonal

12-1131 Datasheet

Price

£512.00

-

Quantity
Unit Size

Find out about delivery