Anti-Cytokeratin 8/18 Recombinant Mouse Monoclonal Antibody (Clone:rKRT8.18/1346)

Catalogue Number: 12-1162-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein; CK18; CYK18 Cytokeratin Endo B; K18; Keratin-18; Kerd; KRT18
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rKRT8.18/1346
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human KRT8 protein and recombinant full-length human KRT18 protein
Application:	IHC

Overview
Datasheets

Description

Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

Additional Text

Purification

Protein A/G Purified

Uniprot ID

P05783, P05787

Gene ID

3856; 3875

Application Notes

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Gene Name

KRT18, KRT8

Antibody Clonality

Monoclonal, Recombinant Monoclonal

12-1162 Datasheet

Price

£512.00

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