Anti-Cytokeratin, Multi (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rKRT/457)
Catalogue Number: 12-1166-ABO
12-1166 Image
12-1166 Image
12-1166 Image
Figure 1: Formalin-fixed, paraffin-embedded human Skin stained with Multi-Cytokeratin Mouse Recombinant Monoclonal Antibody (rKRT/457).
12-1166 Image
Figure 2: SDS-PAGE Analysis Purified Multi-Cytokeratin Mouse Recombinant Monoclonal Antibody (rKRT/457).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rKRT/457 |
| Isotype: | IgG1, kappa |
| Immunogen: | Keratin-enriched preparation from cultured human epithelial cells |
| Application: | IHC |
Description
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI<5.7) and basic (pI>6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Additional Text
Purification
Protein A/G Purified
Uniprot ID
P02538
Application Notes
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Antibody Clonality
Monoclonal, Recombinant Monoclonal
Gene ID
3851; 3852; 3853; 3854
Gene name
KRT4, KRT5, KRT6A, KRT6B
12-1166 Datasheet
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