Anti-Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rEGP40/1372)

Catalogue Number: 12-1176-ABO

Manufacturer:Abeomics
Shelf Life:24 months
Type:Recombinant Monoclonal
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Host name: Mouse
Clone: rEGP40/1372
Isotype: IgG1, kappa
Immunogen: Recombinant ECD-fragment of human EpCAM protein (around aa 77-202) (exact sequence is proprietary)
Application: WB, IHC

Description

Description: EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Additional Text

Gene ID

4072

Gene Name

EPCAM

Uniprot ID

P16422

Purification

Protein A/G Purified

Application Notes

Western Blot (1-2µg/ml); ,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)

Antibody Clonality

Monoclonal, Recombinant Monoclonal

Specificity

Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TROP1; Tumor-associated Calcium Signal Transducer 1 (TACSTD1); ECS-1; Epidermal Surface Antigen 1; ESA1; FLOT2; Flotillin-2.