Anti-Kappa Light Chain (B-Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:rL1C1)
Catalogue Number: 12-1203-ABO
12-1203 Image
12-1203 Image
12-1203 Image
Figure 1: Formalin-fixed, paraffin-embedded human Tonsil stained with Kappa Light Chain Mouse Recombinant Monoclonal Antibody (rL1C1).
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Figure 2: SDS-PAGE Analysis Purified Kappa Light Chain Mouse Recombinant Monoclonal Antibody (rL1C1).
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rL1C1 |
| Isotype: | IgG1, kappa |
| Immunogen: | Human B-Lymphoma Cells |
| Application: | IHC |
Description
Description: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Additional Text
Purification
Protein A/G Purified
Gene Name
IGKC
Gene ID
3514
Application Notes
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Antibody Clonality
Monoclonal, Recombinant Monoclonal
12-1203 Datasheet
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