Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Recombinant Mouse Monoclonal Antibody (Clone:rCDH16/1071)

Catalogue Number: 12-1207-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	Cadherin-16 (CDH16); Kidney-specific cadherin; Ksp-cadherin antibody
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rCDH16/1071
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human CDH16 protein
Application:	FACS, WB, IHC

Overview
Datasheets

Description

Description: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is sµggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been sµggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Additional Text

Gene Name

CDH16

Gene ID

1014

Uniprot ID

O75309

Purification

Protein A/G Purified

Application Notes

Flow Cytometry (1-2µg/million cells); Western Blot (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Antibody Clonality

Monoclonal, Recombinant Monoclonal

12-1207 Datasheet

Price

£512.00

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