Anti-MART-1 / Melan-A / MLANA (Melanoma Marker) Recombinant Mouse Monoclonal Antibody (Clone:rMLANA/1905)
Catalogue Number: 12-1209-ABO
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rMLANA/1905 |
| Isotype: | |
| Immunogen: | Recombinant full-length human MART-1 protein |
Description
Description: This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Additional Text
Gene ID
2315
Gene Name
MLANA
Uniprot ID
Q16655
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal, Recombinant Monoclonal
12-1209 Datasheet
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