Anti-Moesin Recombinant Mouse Monoclonal Antibody (Clone:rMSN/492)

Catalogue Number: 12-1213-ABO

Manufacturer:	Abeomics
Shelf Life:	24 months
Type:	Recombinant Monoclonal
Alias:	Membrane-organizing extension spike protein; Moesin/anaplastic lymphoma kinase fusion protein; MSN/ALK fusion
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	rMSN/492
Isotype:	IgG1, kappa
Immunogen:	Recombinant full-length human Moesin protein
Application:	FACS, IF, WB, IHC

Overview
Datasheets

Description

Description: Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Additional Text

Gene Name

MSN

Purification

Protein A/G Purified

Gene ID

4478

Uniprot ID

P26038

Application Notes

Flow Cytometry (1-2µg/million cells); Immunofluorescence (2-4µg/ml); Western Blot (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

Antibody Clonality

Monoclonal, Recombinant Monoclonal

12-1213 Datasheet

Price

£512.00

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