Anti-PAX5 / BSAP (Early B-Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:rPAX5/2060)

Catalogue Number: 12-1237-ABO

Manufacturer:Abeomics
Shelf Life:24 months
Type:Recombinant Monoclonal
Alias:B cell lineage specific activator; BSAP; EBB-1; KLP; Paired box 5
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug
Host name: Mouse
Clone: rPAX5/2060
Isotype: IgG1, kappa
Immunogen: Recombinant full-length human PAX5 protein
Application: ELISA, WB

Description

Description: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thoµght to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Additional Text

Gene ID

5079

Gene Name

PAX5

Uniprot ID

Q02548

Purification

Protein A/G Purified

Application Notes

ELISA (For coating, purchase antibody without BSA); Western Blot (1-2µg/ml)

Antibody Clonality

Monoclonal, Recombinant Monoclonal