Anti-Villin (GI-Mucosal & Urogenital Brush Border Marker) Recombinant Mouse Monoclonal Antibody (Clone:rVIL1/1325)
Catalogue Number: 12-1264-ABO
| Manufacturer: | Abeomics |
| Shelf Life: | 24 months |
| Type: | Recombinant Monoclonal |
| Alias: | VIL1; Villin-1; Villin1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | rVIL1/1325 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant fragment of human Villin (aa 179-311) (exact sequence is proprietary) |
| Application: | IHC |
Description
Description: Recognizes a protein of 95kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
Additional Text
Gene Name
VIL1
Purification
Protein A/G Purified
Gene ID
7429
Uniprot ID
P09327
Application Notes
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Antibody Clonality
Monoclonal, Recombinant Monoclonal
12-1264 Datasheet
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