Phospho-MCM2 (Ser139) (Clone: B12) rabbit mAb PE conjugate
Catalogue Number: 12-4330-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, CCNL1, CDCL1, KIAA0030 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 tests, 100 tests |
| Host name: | Rabbit |
| Clone: | MCM2S139-B12 |
| Isotype: | IgG1, kappa |
| Immunogen: | A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho MCM2 |
| Application: | FACS |
Description
Description: The members of minichromosome maintenance (McM) protein family 2-7 were originally identified as a group of proteins essential for DNA replication (chromosomal maintenance (1,2). They share common sequence homology to each other in their nulceotide-binding domains and are distinct subgroup of the large AAA ATPase family, which are required for the initiation and elongation of DNA replication. It has been reported that Cdc7/Dbf4 phospohrylates MCM2 during G1/S cell cycle which coincides with the intiation of DNA replication (3,4)
Additional Text
Antibody Clonality
Monoclonal
Application Notes
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
12-4330 Datasheet
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