Anti-CCR8 antibody(DM197), Rabbit mAb
Catalogue Number: 12-9107-ABO
| Manufacturer: | Abeomics |
| Type: | Recombinant Monoclonal |
| Alias: | CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | DM197 |
| Isotype: | IgG |
| Immunogen: | Recombinant human CCR8(Met1-Lys35) produced by using human HEK293 cells |
| Application: | ELISA, FACS |
Description
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Application Notes
ELISA 1/5000-10000;Flow Cyt 1/100
12-9107 Datasheet
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