PE/iFluor® 700 Anti-human CD200 Antibody *OX-104*
Catalogue Number: 120001X0-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 tests |
| Host name: | Mouse |
| Clone: | OX-104 |
| Isotype: | IgG1, kappa |
| Immunogen: |
Description
Description: OX-104 is an anti-human monoclonal antibody that forms an immune complex with the CD200 antigen. CD200 (sometimes referred to as OX-2 or OX2) is a single-pass type i membrane protein that is expressed on the surface of cells like stem cells, dendritic cells, B cells and endothelial cells. CD200 has been thought to be involved with vital biological processes such as cell-cell adhesion, especially heterotypic cell-cell adhesion. In addition, in many organisms, it suppresses neuron death, is a negative regulator of macrophage activation and is a negative regulator of interleukin-6 secretion. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands such as CD200R1. CD200 is a fairly uncommon antibody target, with a little more than 2000 publications in the last decade. Even still, CD200 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of neuroscience and immunology. This antibody was purified through affinity chromatography and conjugated to PE/iFluor® 700 (ex/em = 566/708 nm). It is compatible with the 561 nm laser and 720/60 nm bandpass filter (for example, as in the Bio-Rad ZE5 Cell Analyzer).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
120001X0 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations