ANK1 (Ankyrin-1, Ankyrin 1, ANK-1, Ankyrin-R, Erythrocyte Ankyrin, ANK) (MaxLight 650)
Catalogue Number: 123328-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3C3 |
| Isotype: | IgG2a, kappa |
| Immunogen: | Full length recombinant corresponding to aa1-155 from human ANK1 (AAH30957) with GST tag. MW of the GST tag alone is 26kD. |
| Application: | IP, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin actin cytoskeleton and therefore play a role in cell motility, proliferation and intercellular contact. Different isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains. Ankyrin 1, the prototype of this family, was first discovered in erythrocytes but has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated with hereditary spherocytosis. Different isoforms of ankyrin 1 have been described. Alternative polyadenylation accounting for the different sized erythrocytic ankyrin 1 mRNAs, has also been reported.
Additional Text
Specificity
Recognizes human ANK1.
Purification
Protein A purified
Accession Number
BC030957
Antibody Clonality
Monoclonal
123328-ML650 Datasheet
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