BAIAP2 (Brain-specific Angiogenesis Inhibitor 1-associated Protein 2, BAI1-associated Protein 2, BAI-associated Protein 2, Protein BAP2, Insulin Receptor Substrate Protein of 53kD, Insulin Receptor Substrate p53, IRSp53, Insulin Receptor Substrate p53/p58
Catalogue Number: 123820-PE-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3F3-2D3 |
| Isotype: | IgG2b, kappa |
| Immunogen: | Full length recombinant corresponding to aa1-512 from BAIAP2 (AAH32559) with GST tag. MW of the GST tag alone is 26kD. |
| Application: | ELISA, IP, WB |
Description
Description: BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Additional Text
Accession Number
BC032559
Specificity
Recognizes human BAIAP2.
Purification
Protein A purified
Antibody Clonality
Monoclonal
Full Name
BAIAP2 (Brain-specific Angiogenesis Inhibitor 1-associated Protein 2, BAI1-associated Protein 2, BAI-associated Protein 2, Protein BAP2, Insulin Receptor Substrate Protein of 53kD, Insulin Receptor Substrate p53, IRSp53, Insulin Receptor Substrate p53/p58, IRSp53/58, IRS-58, Fas Ligand-associated Factor 3, FLAF3) (PE)
123820-PE Datasheet
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