BRMS1 (Breast Cancer Metastasis-suppressor 1) (MaxLight 650)

Catalogue Number: 124008-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2D4-2G11
Isotype: IgG1, kappa
Immunogen: Full length recombinant corresponding to aa1-246, from human BRMS1 (AAH09834) with GST tag. MW of the GST tag alone is 26kD.
Application: IP, WB, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Additional Text

Accession Number

AAH09834

Specificity

Recognizes human BRMS1.

Purification

Protein A purified

Antibody Clonality

Monoclonal