CD31 (PECAM-1, Platelet Endothelial Cell Adhesion Molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1) (MaxLight 650)

Catalogue Number: 124607-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD31|CD31 antigen|CD31/EndoCAM|endoCAM|GPIIA'|PECA1|PECAM-1|platelet endothelial cell adhesion molecule|platelet endothelial cell adhesion molecule-1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1D2-1A5
Isotype: IgG1, kappa
Immunogen: Full length recombinant corresponding to aa29-739 from human PECAM1 (AAH22512) with GST tag. MW of the GST tag alone is 26kD.
Application: IP, WB, IHC, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD31 is a 130-140kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (av b3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. This antibody has been shown to inhibit in vitro and in vivo functions of CD31.

Additional Text

Gene Name

PECAM1

Gene ID

5175

Uniprot ID

P16284

Specificity

Recognizes human PECAM1.

Purification

Protein A purified

Accession Number

BC022512

Antibody Clonality

Monoclonal