Catalogue Number: 124607-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD31|CD31 antigen|CD31/EndoCAM|endoCAM|GPIIA'|PECA1|PECAM-1|platelet endothelial cell adhesion molecule|platelet endothelial cell adhesion molecule-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 1D2-1A5 |
| Isotype: | IgG1, kappa |
| Immunogen: | Full length recombinant corresponding to aa29-739 from human PECAM1 (AAH22512) with GST tag. MW of the GST tag alone is 26kD. |
| Application: | IP, WB, IHC, FLISA |
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD31 is a 130-140kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (av b3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis. This antibody has been shown to inhibit in vitro and in vivo functions of CD31.
PECAM1
5175
P16284
Recognizes human PECAM1.
Protein A purified
BC022512
Monoclonal