CES2 (Cocaine Esterase, Carboxylesterase 2, CE-2, hCE-2, Methylumbelliferyl-acetate Deacetylase 2, ICE, CES2A1)

Catalogue Number: 124881-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2.
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 4F12
Isotype: IgG2b, kappa
Immunogen: Partial recombinant corresponding to aa514-622 from CES2 (NP_003860) with GST tag. MW of the GST tag alone is 26kD.
Application: ELISA, IP, WB, IHC

Description

Description: CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

Additional Text

Caution

FOR RESEARCH USE ONLY

Specificity

Recognizes human CES2.

Purification

Protein A purified

Accession Number

NM_003869

Antibody Clonality

Monoclonal