Catalogue Number: 13-0012-EPC
|Shelf Life:||24 months|
|Type:||Polyclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Dry Ice|
|Immunogen:||KLH-conjugated peptide with the sequence KRGRGRGRG in which arg residues were symmetrically dimethylated.|
Description: Symmetric dimethylation of arginine (SDMA) is a post-translational modification catalyzed by type II arginine methyltransferase enzymes and found on many proteins,including those involved in transcriptional regulation, mRNA splicing, DNA repair and nuclear transport. Sym10 recognizes SDMA present at GAR (glycine-arginine rich sequences).
Sym10 antibody is useful for Western blotting (1:500 - 1:2,000 dilution) to detect SDMA on a variety proteins.