iFluor® 700 Anti-human CD300a Antibody *MEM-260*
Catalogue Number: 130000J1-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 tests |
| Host name: | Mouse |
| Clone: | MEM-260 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IF |
Description
Description: MEM-260 is an anti-human monoclonal antibody that is specific for the CD300a antigen. CD300a (alternatively called CLM-8) is a transmembrane protein that is expressed on the surface of cells such as macrophages, T cells, dendritic cells and B cells. In some organisms, CD300a is a repressor of MyD88-dependent toll-like receptor signaling pathway, suppresses B cell receptor signaling pathway and is a promoter of phosphoprotein phosphatase activity. Also, it is a member of important cellular pathways, for example, the negative regulation of B cell receptor signaling pathway, negative regulation of MyD88-dependent toll-like receptor signaling pathway and regulation of T cell receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands like unknown. CD300a is a relatively rare antibody target, with fewer than 400 publications in the last decade. Even still, CD300a is essential for innate immunity and immunology research, commonly serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to iFluor® 700 (ex/em = 690/713 nm).
Additional Text
Antibody Clonality
Monoclonal
Storage Note
See Protocol|12 months
130000J1 Protocol
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations