SOX10 (Transcription Factor SOX-10, MGC15649) (MaxLight 490)

Catalogue Number: 133713-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1E6
Isotype: IgG2a, kappa
Immunogen: Partial recombinant corresponding to aa336-434 from human SOX10 (NP_008872) with GST tag. MW of the GST tag alone is 26kD.
Application: WB, IHC, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Additional Text

Specificity

Recognizes human SOX10.

Purification

Protein A purified

Accession Number

NM_006941

Antibody Clonality

Monoclonal