SPI1 (Transcription Factor PU.1, 31kD-transforming Protein) (MaxLight 490)

Catalogue Number: 133772-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2G1
Isotype: IgG1, kappa
Immunogen: Partial recombinant corresponding to aa1-121 from human SPI1 (NP_003111) with GST tag. MW of the GST tag alone is 26kD.
Application: IF, WB, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

Additional Text

Specificity

Recognizes human SPI1. Species Crossreactivity: mouse.

Purification

Protein A purified

Accession Number

NM_003120

Antibody Clonality

Monoclonal