SPR (Sepiapterin Reductase (7,8-Dihydrobiopterin:NADP+ Oxidoreductase, SDR38C1) (MaxLight 490)
Catalogue Number: 133799-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 4F2 |
| Isotype: | IgG2a, kappa |
| Immunogen: | Partial recombinant corresponding to aa164-261 from human SPR (NP_003115) with GST tag. MW of the GST tag alone is 26kD. |
| Application: | IP, WB, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Additional Text
Specificity
Recognizes human SPR.
Purification
Protein A purified
Accession Number
NM_003124
Antibody Clonality
Monoclonal
133799-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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