SRC (Proto-oncogene Tyrosine-protein Kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC1) (MaxLight 490)
Catalogue Number: 133823-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 1B9 |
| Isotype: | IgG2a, kappa |
| Immunogen: | Partial recombinant corresponding to aa1-90 from human SRC (AAH11566) with GST tag. MW of the GST tag alone is 26kD. |
| Application: | WB, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Additional Text
Specificity
Recognizes human Src.
Purification
Protein A purified
Accession Number
BC011566
Antibody Clonality
Monoclonal
133823-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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