SSH1 (Protein Phosphatase Slingshot Homolog 1, SSH-like Protein 1, SSH1L, SSH-1L, hSSH-1L, KIAA1298) (MaxLight 490)

Catalogue Number: 133860-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2F9
Isotype: IgG2a, kappa
Immunogen: Partial recombinant corresponding to aa752-850 from human SSH1 (NP_061857) with GST tag. MW of the GST tag alone is 26kD.
Application: WB, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).

Additional Text

Specificity

Recognizes human SSH1.

Purification

Protein A purified

Accession Number

NM_018984

Antibody Clonality

Monoclonal