STAT2 (Signal Transducer and Activator of Transcription 2, p113, MGC59816) (MaxLight 490)

Catalogue Number: 133932-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	5G7
Isotype:	IgG1, kappa
Immunogen:	Partial recombinant corresponding to aa742-851 from human STAT2 (AAH51284) with GST tag. MW of the GST tag alone is 26kD.
Application:	IF, WB, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Additional Text

Specificity

Recognizes human STAT2.

Purification

Protein A purified

Accession Number

BC051284

Antibody Clonality

Monoclonal

133932-ML490 Datasheet

Price

£896.00

-

Quantity
Unit Size

Find out about delivery