STAT5A (Signal Transducer and Activator of Transcription 5A, STAT5) (MaxLight 490)

Catalogue Number: 133938-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1B12
Isotype: IgG1, kappa
Immunogen: Partial recombinant corresponding to aa1-104 from human STAT5A (AAH27036) with GST tag. MW of the GST tag alone is 26kD.
Application: WB, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Two highly related, but distinct STAT5 genes (STAT5a and STAT5b) were identified in mice. The aa sequences of Stat5a and Stat5b show approximately 96% sequence similarity, and both proteins are co-expressed in most tissues of both virgin and lactating mice. However, differential accumulation of STAT5a and STAT5b in mRNA has been reported for both muscle and mammary tissue. STAT5 has been shown to be the essential mediator of prolactin induced milk protein gene activation. This antibody detects Stat5 a/b.

Additional Text

Specificity

Recognizes human STAT5A.

Purification

Protein A purified

Accession Number

BC027036

Antibody Clonality

Monoclonal