TAF6L (TAF6-like RNA Polymerase II p300/CBP-associated Factor-associated Factor 65kD Subunit 6L, PCAF-associated Factor 65-alpha, PAF65-alpha, PAF65A) (MaxLight 490)

Catalogue Number: 134194-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	1C5
Isotype:	IgG2b, kappa
Immunogen:	Partial recombinant corresponding to aa2-109 from TAF6L (NP_006464) with GST tag. MW of the GST tag alone is 26kD.
Application:	IF, WB, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.

Additional Text

Specificity

Recognizes human TAF6L.

Purification

Protein A purified

Accession Number

NM_006473

Antibody Clonality

Monoclonal

134194-ML490 Datasheet

Price

£896.00

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