TBX6 (T-box Transcription Factor TBX6, T-box Protein 6) (MaxLight 490)

Catalogue Number: 134269-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2D11
Isotype:	IgG2b, kappa
Immunogen:	Partial recombinant corresponding to aa191-300 from human TBX6 (NP_004599) with GST tag. MW of the GST tag alone is 26kD.
Application:	IF, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. T-box transcription factors contain a novel type of DNA-binding domain, the T-box domain, which are encoded by an ancient gene family. Four T-box genes, omb, Trg, org-1, and H15, have been identified in Drosophila, whereas in mammals the T-box gene family has expanded, and 12 human T-box genes have been isolated. Most T-box genes have discrete spatial and temporal patterns of expression during embryogenesis. Even though the function of human T-Box gene 6 (TBX6) is still unknown, knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures and required for their normal patterning.

Additional Text

Specificity

Recognizes human TBX6.

Purification

Protein A purified

Accession Number

NM_004608

Antibody Clonality

Monoclonal

134269-ML490 Datasheet

Price

£896.00

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