TCF4 (Transcription Factor 4, TCF-4, Class B Basic Helix-loop-helix Protein 19, bHLHb19, Immunoglobulin Transcription Factor 2, ITF-2, SEF-2, SL3-3 Enhancer Factor 2, BHLHB19, ITF2, SEF2, MGC149723, MGC149724) (MaxLight 490)

Catalogue Number: 134294-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1G4
Isotype: IgG1, kappa
Immunogen: Full length recombinant corresponding to aa1-365 from human TCF4 with GST tag. MW of the GST tag alone is 26kD.
Application: IF, WB, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Additional Text

Specificity

Recognizes human TCF4.

Purification

Protein A purified

Accession Number

BC031056

Antibody Clonality

Monoclonal