TFAP2B (Transcription Factor AP-2-beta, AP2-beta, Activating Enhancer-binding Protein 2-beta, MGC21381) (MaxLight 490)

Catalogue Number: 134351-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3G5-1D11
Isotype: IgG1, kappa
Immunogen: Full length recombinant corresponding to aa1-450 from human TFAP2B (AAH37225) with GST tag. MW of the GST tag alone is 26kD.
Application: IF, WB, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq].

Additional Text

Specificity

Recognizes human TFAP2B.

Purification

Protein A purified

Accession Number

BC037225

Antibody Clonality

Monoclonal