Bax (BCL2-associated X protein, Apoptosis regulator BAX, BAX protein, BCL2L4, Bcl-2-like Protein 4, Bcl2-L-4) (MaxLight 490)

Catalogue Number: 138495-AF-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	apoptosis regulator BAX\|Baxdelta2G9\|Baxdelta2G9omega\|Baxdelta2omega\|BCL2 associated X protein\|BCL2-associated X protein omega\|BCL2L4\|bcl2-L-4\|bcl-2-like protein 4
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2D2
Isotype:	IgG1
Immunogen:	Synthetic peptide corresponding to aa3-16 (Cys-GSGEQPRGGGPTSS) from human Bax.
Application:	IF, IP, WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Recognizes a protein of 21kD, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2a or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Additional Text

Gene Name

BAX

Gene ID

581

Uniprot ID

Q07812

Accession Number

NP_004315

Specificity

Recognizes human Bax. Species Crossreactivity: monkey. Does not react with mouse or rat.

Purification

Protein G purified

Antibody Clonality

Monoclonal

138495-AF-ML490 Datasheet

Price

£883.00

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Quantity
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