Bax (BCL2-associated X protein, Apoptosis regulator BAX, BAX protein, BCL2L4, Bcl-2-like Protein 4, Bcl2-L-4)
Catalogue Number: 138495-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | 2D2 |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to aa3-16 (Cys-GSGEQPRGGGPTSS) from human Bax. |
| Application: | ELISA, FC, IF, IP, WB, IHC |
Description
Description: Recognizes a protein of 21kD, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2a or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Additional Text
Gene Name
BAX
Gene ID
581
Uniprot ID
Q07812
Accession Number
NP_004315
Purification
Protein G purified
Antibody Clonality
Monoclonal
138495 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations