CD31 (PECAM-1, EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA) (MaxLight 490)
Catalogue Number: 138510-AF-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | C31.7 |
| Isotype: | IgG1, kappa |
| Immunogen: | Full-length recombinant protein corresponding to human CD31. Cellular Localization: Cell junction, cell membrane, membrane raft |
| Application: | FC, IF, WB, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Additional Text
Gene Name
PECAM1
Gene ID
5175
Uniprot ID
P16284
Accession Number
NP_000433
Purification
Protein A/G Purified
Specificity
Recognizes human CD31. Species Crossreactivity: Cynomolgus monkey and rabbit
Antibody Clonality
Monoclonal
138510-AF-ML490 Datasheet
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
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