CD34 (Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin) (PE)
Catalogue Number: 138512-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | ICO-115 |
| Isotype: | IgG1, kappa |
| Immunogen: | Blast cells of a chronic myeloid leukemia patient. Cellular Localization: Cell surface |
| Application: | FC, IF |
Description
Description: This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kD, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells.
Additional Text
Accession Number
NP_001020280
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
138512 Datasheet
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