Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, Vasostatin) (MaxLight 490)

Catalogue Number: 138532-AF-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	betagranin (N-terminal fragment of chromogranin A)\|catestatin\|CGA\|chromofungin\|chromogranin-A\|parathyroid secretory protein 1\|pituitary secretory protein I\|SP-I
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	CGA414
Isotype:	IgG1, kappa
Immunogen:	Recombinant protein fragment corresponding to human Chromogranin A.
Application:	IF, IP, WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and othe r neuroendocrine tumors. Co- expression of chromogranin A and neuron specific enolase (NS E) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining a nd absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolacti nomas readily express chromogranin.

Additional Text

Gene ID

1113

Gene Name

CHGA

Uniprot ID

P10645

Accession Number

NP_001266

Specificity

Recognizes human chromogranin A.

Purification

Protein G purified

Antibody Clonality

Monoclonal

138532-AF-ML490 Datasheet

Price

£883.00

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Quantity
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