MART-1 (Melanoma Antigen Recognize by T cells 1, Melan-A) (MaxLight 490)

Catalogue Number: 138568-AF-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	antigen LB39-AA\|antigen SK29-AA\|epididymis secretory sperm binding protein\|MART1\|MART-1\|melanoma antigen recognized by T-cells 1\|protein Melan-A
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	M2-7C10
Isotype:	IgG2b, kappa
Immunogen:	Recombinant protein corresponding to human MART-1.
Application:	IF, IP, WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This antibody recognizes a protein doublet of 20-22kD, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is pres ent in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Additional Text

Gene ID

2315

Gene Name

MLANA

Uniprot ID

Q16655

Accession Number

NP_005502

Specificity

Recognizes human MART-1. Does not react with mouse or rat.

Purification

Protein G purified

Antibody Clonality

Monoclonal

138568-AF-ML490 Datasheet

Price

£883.00

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Quantity
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