Mucin 2 (MUC2, Mucin-2) (MaxLight 490)
Catalogue Number: 138573-AF-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | CCP58 |
| Isotype: | IgG1, kappa |
| Immunogen: | Synthetic peptide corresponding to 29aa, KYPTTTPISTTTMVTPTPTPTGTQTPTTT, from MUC2, coupled to KLH. |
| Application: | IF, IP, WB, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Recognizes a single glycoprotein of 520kD, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Additional Text
Accession Number
NP_002448
Specificity
Recognizes human MUC2.
Purification
Protein G purified
Uniprot ID
Q02817
Antibody Clonality
Monoclonal
138573-AF-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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