Podocalyxin (Podocalyxin-like Protein, PDXL) (MaxLight 490)
Catalogue Number: 138585-AF-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | GCTM-2 antigen|Gp200|PC|PCLP|PCLP-1|podocalyxin|podocalyxin-like protein 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3D3 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin. Epitope: extracellular domain |
| Application: | IF, IP, WB, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidne y development and homeostasis, blood filtration and urine formation. It is also expressed on va scular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturi a) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Additional Text
Gene Name
PODXL
Accession Number
NP_001018121
Specificity
Recognizes human podocalyxin. Species Crossreactivity: rabbit and rat.
Uniprot ID
O00592
Gene ID
5420
Purification
Purified
Antibody Clonality
Monoclonal
138585-AF-ML490 Datasheet
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