Secretory Component (MaxLight 490)

Catalogue Number: 138594-AF-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Alias:extracellular matrix protein 1|secretory component p85|testicular tissue protein Li 61|URBWD
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: SC05 (or COMPO2)
Isotype: IgG1, kappa
Immunogen: Secretory Component protein isolated from human colostrum
Application: IF, IP, WB, IHC, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This monoclonal antibody reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

Additional Text

Gene Name

ECM1

Accession Number

NP_001189787

Specificity

Recognizes human secretory component. Species Crossreactivity: rat.

Purification

Protein G purified

Uniprot ID

Q16610

Gene ID

1893

Antibody Clonality

Monoclonal