IL10 (Interleukin-10, IL-10, Interleukin 10, Cytokine Synthesis Inhibitory Factor, CSIF) (MaxLight 490)
Catalogue Number: 143595-ML490-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 14G8 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant human IL-10 expressed in E.coli. |
| Application: | WB, IHC, FLISA, NT |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
143595-ML490 Datasheet
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