Interleukin 27 (IL-27/IL-35 EBI3 Subunit) (PerCP)

Catalogue Number: 145496-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide. Labeled with PerCP.
Type:Monoclonal Primary Antibody - Conjugated
Alias:EBI-3|epstein-Barr virus-induced gene 3 protein homolog|IL-27|IL-27 subunit beta|IL-27B|interleukin-27 subunit beta
Shipping Condition:Blue Ice
Unit(s): 100 Tests
Host name: Rat
Clone: 355022
Isotype: IgG2a
Immunogen: Recombinant protein corresponding to aa19-228 from mouse Interleukin 27, NS0-derived (Accession# NP_056581).
Application: FC

Description

Description: Interleukin 27 (IL-27) is a heterodimeric cytokine comprised of the IL-12 p35-related protein, p28, and the IL-12 p40-related protein, EBI3 (Epstein-Barr virus-induced gene 3). IL-27 binds TCCR/WSX-1 on naive CD4+ T cells and induces the expression of a functional IL-12 receptor, making these cells sensitive to IL-12-mediated Th1 cell development.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

EBI3

Gene ID

50498

Specificity

Recognizes mouse Interleukin 27.

Accession Number

NP_056581

Purification

Protein A purified

Uniprot ID

O35228

Antibody Clonality

Monoclonal