BRD2 Bromodomain 1

Catalogue Number: 15-0009-EPC

Manufacturer:EpiCypher
Shelf Life:6 months
Type:Fusion Protein
Host Cell:E.coli
Shipping Condition:Dry Ice
Unit(s): 100 ug

Description

Description: Recombinant human BRD2 Bromodomain 1 (RING3, accession number P25440, amino acids 57 to 200) containing an N-terminal GST tag, expressed in E. coli. BRD2 is a member of the BET sub-family of bromodomain-containing proteins, which also includes BRD3, BRD4 and BRDT. BET proteins have two bromodomains and an ET domain C-terminal to the second bromodomain. BRD2 has been reported to bind multiple sites of acetylation on histone H4. BRD2 is essential for mammalian development, and has been linked to Juvenile Myoclonic Epilepsy.

Additional Text

Protein Tag

GST Tag

Application Notes

Recombinant BRD2 Bromodomain 1 is useful for protein binding and screening experiments examining acetylated protein substrates.

Storage Note

Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.