Histone H2AZ.1, Recombinant Human
Catalogue Number: 15-0305-EPC
| Manufacturer: | EpiCypher |
| Shelf Life: | 6 months |
| Physical state: | Lyophilized |
| Type: | DNA Binding Proteins |
| Host Cell: | E.coli |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
| Host name: | Human |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Recombinant human histone H2AZ.1 (H2A.Z; H2AFZ; P0C0S5) expressed in E. coli and purified by FPLC. Histone variants H2AZ.1 and H2AZ.2 (H2A.V; H2AF.V; Q71UI9) differ by three amino acids and are incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AZ is implicated in diverse functions ranging from transcriptional regulation, chromosome transmission and DNA damage repair. H2AZ has a dedicated deposition machinery (the SWR-C ATPase) and is acetylated by the KAT5/TIP60 complex.
Additional Text
Protein Tag
Untagged
Application Notes
Recombinant histone H2AZ.1 is suitable for enzyme assays and nucleosome reconstitution. Reconstitute with distilled water or suitable buffer prior to usage.
Storage Note
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
Preparation
lyophilized|100 µg lyophilized protein in a screw cap plastic vial
15-0305 Datasheet
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