Histone H2AX, Recombinant Human
Catalogue Number: 15-0307-EPC
| Manufacturer: | EpiCypher |
| Shelf Life: | 6 months |
| Physical state: | Lyophilized |
| Type: | DNA Binding Proteins |
| Host Cell: | E.coli |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
| Host name: | Human |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Recombinant human histone H2AX (H2AFX, accession P16104) expressed in E. coli and purified by FPLC. Histone H2AX is a histone variant that is incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AX is phosphorylated on serine 139 by the ATM and ATR kinases in response to DNA double strand breakage. Phosphorylated H2AX serves as a platform to recruit a number of DNA damage repair proteins, including BRCA1, NBS1 and MDC1.
Additional Text
Gene ID
3014
Uniprot ID
P16104
Protein Tag
Untagged
Application Notes
Recombinant histone H2AX is suitable for enzyme assays and nucleosome reconstitution. Reconstitute with distilled water or suitable buffer prior to usage. Purity >93% as measured by chromatogram analysis.
Gene Name
H2ax
Storage Note
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
Preparation
lyophilized|100 µg lyophilized protein in a screw cap plastic vial
15-0307 Datasheet
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