Histone Octamer, Recombinant Human

Catalogue Number: 16-0001-EPC

Shelf Life:6 months
Type:DNA Binding Proteins
Shipping Condition:Dry Ice
Unit(s): 50 ug


Description: Human histone octamers (two each of histones H2A, H2B, H3 and H4) made from recombinant histones expressed in E. coli (accession numbers: H2A-P04908; H2B-O60814; H3.1-P68431; H4-P62805). The histone octamer is the protein component of the nucleosome, the basic subunit of chromatin. A nucleosome consists of a histone octamer wrapped with 147 base pairs of DNA (note that there is only histone octamer in this product).

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Application Notes

Human recombinant histone octamers can be used for chromatin reconstitution experiments, or as substrates for histone modifying enzymes. See product page on web for links to protocols for chromatin reconstitution. Histone octamers should not be stored under conditions where the salt concentration is lower than 800 mM. Please note that the concentration may vary compared to previous lots.