BPI, Human Neutrophil

Catalogue Number: 16-14-021609-ART

Manufacturer:Athens Research
Preservative:Frozen in 80 mM Citrate Phosphate, pH 5.6, 700-750 mM NaCl.
Molecular Weight:55000
Ph:pH 5.6
Physical state:Frozen
Type:Protease Inhibitor Protein
Shipping Condition:Dry Ice
Storage Condition:-70°C
Unit(s): 100 ug

Description

Description: Bacterial/Permeability-Increasing Protein (BPI) is present in the azurophilic granules of polymorphonuclear leukocytes (PMN). BPI is toxic only toward Gram-negative bacteria. This specificity is attributable to the strong attraction of BPI for the lipopolysaccharides (LPS) in the bacterial envelope. BPI is also an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis.